Abstract

Abstract The struggle over credit for the discovery of insulin serves as one of the ugliest examples of the tensions and rivalries inherent in the growth of large-scale laboratory science. An understanding of this historic controversy also lends insight into the use of informal self-narratives directed to the scientifıc community in the negotiation of credit for discovery. Such informal accounts constitute a distinct form of argumentative address that is separate both from formal oral and written presentations of research, also aimed at a scientifıc audience, and popularized accounts aimed at a lay audience. In providing informal self-narratives to their scientifıc peers, the four insulin principals discussed in this article apparently shared a tacit understanding of the narrative grounds on which they could base their claims for discovery credit. In this study, we uncover widespread thematic similarities within these narratives, possibly indicating a common set of criteria within the scientifıc community for judging not only formal scientifıc proof but also the narrative proof found in informal discovery accounts.

Journal
Rhetoric & Public Affairs
Published
2020-03-01
DOI
10.14321/rhetpublaffa.23.1.0001
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References (156) · 2 in this index

  1. 1. Frederick G. Banting, Diabetes and Insulin: Nobel Lecture Delivered at Stockholm on September 15, 1925 (St…
  2. 2. Michael Bliss, The Discovery of Insulin (Chicago, IL: University of Chicago Press, 1982), 11, 25–27.
  3. 3. Bliss, Discovery of Insulin, 28–29.
  4. 4. Frederick G. Banting, “The History of Insulin,” Cameron Prize Lecture, Pamphlet reprinted from the Edinbur…
  5. 5. Banting, Diabetes and Insulin, 2.
Show all 156 →
  1. 6. Michael Bliss, “Special Lecture: J. J. R. Macleod and the Discovery of Insulin,” Quarterly Journal of Expe…
  2. 7. Frederick G. Banting, Letter to Colonel Albert Gooderham, Special Collections, GC/67/2, Wellcome Library, …
  3. 8. One good reproduction of this photograph may be found in Bliss, Discovery of Insulin.
  4. 9. Michael Bliss, “The Eclipse and Rehabilitation of JJR Macleod, Scotland’s Insulin Laureate,” Journal of th…
  5. 10. J. B. Collip, January 8, 1922, quoted in Bliss, Discovery of Insulin, 84.
  6. 11. Bliss, Discovery of Insulin, 11-12, 111-13, 126. Macleod later noted in his Nobel Lecture that the name "…
  7. J. J. R. Macleod, The Physiology of Insulin and Its Source in the Animal Body: Nobel Lecture Delivered at Sto…
  8. 12. Banting, Diabetes and Insulin, 16.
  9. 13. Collip was often circumspect in his discussion of the discovery process, having not been there at the adv…
  10. 14. We further believe that the fraught relationship among the insulin principals, and related charges of the…
  11. 15. Struan Jacobs, “Scientifıc Community: Formulations and Critique of a Sociological Motif,” British Journal…
  12. 16. Walter R. Fisher, Human Communication as Narration: Toward a Philosophy of Reason, Value, and Action (Col…
  13. 17. Lawrence J. Prelli, A Rhetoric of Science: Inventing Scientifıc Discourse (Columbia: University of South …
  14. 18. Bliss, Discovery of Insulin, 229–30. Bliss is largely quoting from an unpublished 1940 memoir by Frederic…
  15. 19. Bliss, Discovery of Insulin, 230.
  16. 20. Bliss, Discovery of Insulin, 230–32.
  17. 21. Michael Bliss, “Banting’s, Best’s, and Collip’s Accounts of the Discovery of Insulin” (introduction), Bul…
  18. 22. Bliss, Discovery of Insulin, 85, 200.
  19. 23. From Banting, we will examine his account to Gooderham (1922), his Nobel Lecture (1923), and his Cameron …
  20. 24. Michael Bliss, “Rewriting Medical History: Charles Best and the Banting and Best Myth,” Journal of the Hi…
  21. 25. Bliss, “Rewriting Medical History,” 257. In 1953, the Best Institute opened at the University of Toronto,…
  22. 26. István Hargittai, The Road to Stockholm: Nobel Prizes, Science, and Scientists (Oxford: Oxford University…
  23. 27. Bliss, “Rewriting Medical History,” 253.
  24. 28. Ultimately, Banting came to have a strong animus toward Best, partly fueled by their butting heads at the…
  25. 29. Bliss, “Special Lecture,” 87.
  26. 30. As Michael Bliss wrote, in celebrating the righting of the insulin record, “No one in 2013 would say that…
  27. 31. Ronald D. Vale and Anthony A. Hyman, “Priority of Discovery in the Life Sciences,” eLife 5 (2016), https:…
  28. 32. Alan G. Gross, “Do Disputes Over Priority Tell Us Anything About Science?” Science in Context 11 (1998): 161.
  29. 33. Augustine Brannigan, The Social Basis of Scientifıc Discoveries (Cambridge: Cambridge University Press, 1…
  30. 34. Richard D. Besel, “Opening the ‘Black Box’ of Climate Change Science: Actor-Network Theory and Rhetorical…
  31. 35. Prelli, A Rhetoric of Science, 110-11. Although scientists' apparent fıdelity may be to the scientifıc co…
  32. and J. M. Ziman, Public Knowledge: An Essay Concerning the Social Dimension of Science (Cambridge: Cambridge …
  33. 36. Michael Mulkay, “The Mediating Role of the Scientifıc Elite,” Social Studies of Science 6 (1976): 446–48.
  34. 37. Prelli, A Rhetoric of Science, 143.
  35. 38. Vale and Hyman, “Priority of Discovery.”
  36. 39. Mulkay, “Mediating Role,” 452, 454.
  37. 40. Michael J. Mulkay, The Social Process of Innovation: A Study in the Sociology of Science (London: MacMill…
  38. 41. Mulkay, The Social Process of Innovation, 23.
  39. 42. Besel, “Opening the ‘Black Box,‘” 125. For the importance of “a balanced negotiation between text and con…
  40. 43. Craig O. Stewart, “Socioscientifıc Controversies: A Theoretical and Methodological Framework,” Communicat…
  41. 44. Bruno Latour and Steve Woolgar, Laboratory Life: The Construction of Scientifıc Facts (Princeton, N.J.: P…
  42. 45. G. Nigel Gilbert and Michael Mulkay, Opening Pandora's Box: A Sociological Analysis of Scientists' Discou…
  43. and, as Anna Da Fina states, our storytelling changes shape as it is "embedd[ed] in social life." Anna De Fin…
  44. 46. Some studies seek the differences between self-narratives directed to a public versus a scientifıc audien…
  45. 47. Gilbert and Mulkay, Opening Pandora’s Box, 15.
  46. 48. Anna De Fina and Alexandra Georgakopoulou, “Introduction: Narrative Analysis in the Shift from Texts to P…
  47. 49. Paul Watzlawick and Janet Beavin, “Some Formal Aspects of Communication,” American Behavioral Scientist 1…
  48. 50. As Watzlawick and Beavin maintain, our very inclination to punctuate events provides ample opportunity fo…
  49. 51. Donald E. Polkinghorne, Narrative Knowing and the Human Sciences (Albany: State University of New York Pr…
  50. 52. Frederick G. Banting, Account to Gooderham, 1.
  51. 53. Banting, Account to Gooderham, 3.
  52. 54. Banting, Account to Gooderham, 4.
  53. 55. Banting, Account to Gooderham, 5–6.
  54. 56. Banting, Account to Gooderham, 7.
  55. 57. As Banting would say in his Cameron Prize Lecture, his goal with a public audience was to “endeavour to t…
  56. 58. J. J. R. Macleod, “History of the Researches Leading to the Discovery of Insulin,” Account sent to Col. A…
  57. 59. Macleod, “History of the Researches,” 6–8.
  58. 60. Macleod, “History of the Researches,” 7.
  59. 61. Macleod, “History of the Researches,” 10.
  60. 62. Oddly, given this nod to chance, Best did not embrace the story that E. C. Noble tossed a coin with him t…
  61. 63. Best, “A Report of the Discovery,” 2.
  62. 64. J. B. Collip, “The History of the Discovery of Insulin,” Northwest Medicine 22 (1923): 267. Later in the …
  63. 65. Collip, “History of the Discovery,” 267. But Collip also positioned the results of the Toronto work “as a…
  64. 66. R. M. Pearce, “Chance and the Prepared Mind,” Science 35 (1912): 941. This famous quote of Pasteur is mos…
  65. 67. John Ziman, An Introduction to Science Studies: The Philosophical and Social Aspects of Science and Techn…
  66. 68. Derek J. de Solla Price, Little Science, Big Science … And Beyond (New York: Columbia University Press, 1…
  67. 69. See, for example, Rebecca M. Herzig, Suffering for Science: Reason and Sacrifıce in Modern America (New B…
  68. 70. Ziman, Introduction to Science Studies, 134. The construction of buildings for research arose with the in…
  69. 71. Kerry Holden, “Lamenting the Golden Age: Love, Labour and Loss in the Collective Memory of Scientists,” S…
  70. 72. Mary Jo Nye, “Mine, Thine, and Ours: Collaboration and Co-Authorship in the Material Culture of the Mid-T…
  71. 73. Nye, “Mine, Thine, and Ours,” 234.
  72. 74. Complicating this tension between the lone and collective scientist may be a sense of whether “discovery”…
  73. 75. Banting, Account to Gooderham, 1; Banting, Diabetes and Insulin, 2.
  74. 76. Christine Trott, “Rhetorical Invention in the Discovery of Insulin,” Technostyle 16 (2000): 52. Trott’s e…
  75. 77. Banting, “History of Insulin,” Cameron Prize Lecture, 17.
  76. 78. Banting, “History of Insulin,” Cameron Prize Lecture, 17.
  77. 79. We would like to thank Leah Ceccarelli for pointing out the romantic/sexual nature of this passage.
  78. 80. Banting, Account to Gooderham, 4–5.
  79. 81. In the Cameron Prize Lecture, after talking about the “kindly and gentle treatment” afforded to the dogs …
  80. 82. Banting, Account to Gooderham, 6.
  81. 83. At times, for Best, the “idea” was crystallized into the form viewed as guiding scientifıc research: “A h…
  82. 84. Best, “A Report of the Discovery,” 2. In separating out his work with Banting from the influence of Macle…
  83. 85. Best, “A Report of the Discovery,” 3.
  84. 86. Macleod, “History of the Researches,” 6–7.
  85. 87. Macleod could easily call Banting and Best on any claims for “the idea of using alcohol at different conc…
  86. 88. Best, “A Report of the Discovery,” 4. Best stated that Collip did the initial glycogen estimation, but he…
  87. 89. Quoted in Nye, “Mine, Thine, and Ours,” 216.
  88. 90. As the head of an insulin team that included Banting and still was working toward a therapeutic outcome, …
  89. 91. J. J. R. Macleod letter to A. V. Hill, 3rd Nov. 1931, 301853, GC/167, Wellcome Library. Macleod was in th…
  90. 92. J. B. Collip, “Recollections of Sir Frederick Banting,” Canadian Medical Association Journal 47 (1942): 4…
  91. 93. Collip, “Recollections of Sir Frederick Banting,” 401.
  92. 94. Banting, Account to Gooderham, 2.
  93. 95. Banting, Account to Gooderham, 2. Macleod put forward his own version of this same move, mentioning that,…
  94. 96. Macleod, “History of the Researches,” 2–3. Primarily, Macleod’s focus was on the belief that “the present…
  95. 97. James W. McAllister, “Rhetoric of Effortlessness in Science,” Perspectives on Science 24 (2016): 145–46.
  96. 98. Banting, Account to Gooderham, 3.
  97. 99. Best, “Discovery of Insulin,” 1947, 17. Best is gracious in acknowledging the contribution of Macleod in …
  98. 100. Best, “Discovery of Insulin,” 1947, 18.
  99. 101. Charles Best, “The Discovery of Insulin,” Proceedings of the American Diabetes Association 6 (1946): 88.
  100. 102. Charles Best, “Reminiscences of the Researches Which Led to the Discovery of Insulin,” Canadian Medical …
  101. 103. Best, “Discovery of Insulin,” 1946, 88.
  102. 104. Best, “Discovery of Insulin,” 1946, 88. Macleod and Collip were not nearly as visual in their recounting…
  103. 105. Macleod, “History of the Researches,” 5. An entire study could be conducted on active and passive voice …
  104. 106. Macleod, “History of the Researches,” 5. Despite these indications of collaboration, Banting repeatedly …
  105. 107. Cathy Sampson and Paul Atkinson, “The Golden Star: An Emotional Repertoire of Scientifıc Discovery and L…
  106. 108. Bliss, Discovery of Insulin, 90–91. Michael Bliss has written that this was an informal meeting and repo…
  107. 109. Banting, Account to Gooderham, 4.
  108. 110. Macleod, “History of the Researches,” 3.
  109. 111. Banting, Account to Gooderham, 4. By prior arrangement, Best was scheduled to show the charts, and that …
  110. 112. Banting, Account to Gooderham, 6. According to Macleod’s Gooderham account, Banting complained to collea…
  111. 113. Nye, “Mine, Thine, and Ours,” 234.
  112. Technical Communication Quarterly
  113. Technical Communication Quarterly
  114. 115. Harris, “Reception Studies,” 249.
  115. 116. Macleod, “History of the Researches,” 5.
  116. 117. Macleod, “History of the Researches,” 6. Macleod regretted allowing Banting and Best to beg off—as too e…
  117. 118. Banting, Account to Gooderham, 10.
  118. 119. Banting, Account to Gooderham, 10.
  119. 120. Occasionally, this disagreement over the prerogatives of the “chief” is stated clearly. In addressing Ba…
  120. 121. Banting, Account to Gooderham, 1.
  121. 122. Banting, Account to Gooderham, 1–4. In a different category was Professor Henderson, who later found Ban…
  122. 123. Macleod, Introductory Letter to Gooderham, 2.
  123. 124. Macleod, Introductory Letter to Gooderham, 2.
  124. 125. Macleod, Introductory Letter to Gooderham, 2.
  125. 126. Macleod, Introductory Letter to Gooderham, 3.
  126. 127. Collip, “Recollections of Sir Frederick Banting,” 401.
  127. 128. J. B. Collip, “Obituary Notices: John James Rickard Macleod,” Biochemistry 29 (1935): 1256.
  128. 129. Collip, “Recollections of Sir Frederick Banting,” 401.
  129. 130. In his Cameron Prize Lecture, Banting shared the award with a “group of workers” whose “whole-hearted as…
  130. 131. Bliss, Discovery of Insulin, 65–66. A more serious fıght was narrowly avoided in January 1922, when Coll…
  131. 132. Macleod, “History of the Researches,” 4.
  132. 133. Collip, “Obituary Notices,” 1256.
  133. 134. Macleod, “History of the Researches,” 3; Macleod, Introductory Letter to Gooderham, 2; and Macleod, “His…
  134. 135. J. B. Collip, “Reminiscences on the Discovery of Insulin,” Journal of the Canadian Medical Association 8…
  135. 136. Macleod, “History of the Researches,” 4. In January 1922, Macleod did step forward in his role as chief …
  136. 137. Alberto de Leiva, Eula’lia Brugués, and Alejandra de Leiva-Pérez, “The Discovery of Insulin: Continued C…
  137. 138. Robert K. Merton, The Sociology of Science: Theoretical and Empirical Investigations (Chicago, IL: Unive…
  138. 139. Bliss, Discovery of Insulin, 87.
  139. 140. Bliss, “Rewriting Medical History,” 273–74.
  140. 141. Letter from J. J. R. Macleod to August Krogh, October 27, 1922, Best (Charles Herbert) Papers, the Disco…
  141. 142. Rosenfeld, “Insulin: Discovery and Controversy,” 2282–84); and Jan Lindsten, “August Krogh and the Nobel…
  142. 143. As early as 1976, Steven Woolgar contemplated the diffıculties in squaring scientifıc accounts of discov…
  143. 144. Gilbert and Mulkay, Opening Pandora’s Box, 11
  144. 145. Wayne Booth introduced the term “unreliable narrator” in 1961 to mean a narrator “discovered to be untru…
  145. 146. Fiona Otway, “The Unreliable Narrator in Documentary,” Journal of Film and Video 67 (2015): 13.
  146. 147. Otway, “Unreliable Narrator,” 8. In fact, as Fiona Otway argues, the very “presence of an unreliable nar…
  147. 148. For example, see Mark Jurdjevic and Caitlin Tillman, "Texts and Documents: E. C. Noble in June 1921, and…
  148. Dimitrios T. Karamitsos, "The Story of Insulin Discovery," Diabetes Research and Clinical Practice 93 (2011): S2-S8
  149. Jesse Roth, Sana Qureshi, Ian Whitford, Mladen Vranic, C. Ronald Kahn, I. George Fantus, and John H. Dirks, "…
  150. 149. Merton, Sociology of Science, 321–22. Lawrence Prelli has written extensively of the way scientists depl…
  151. 150. Carol Reeves, “Owning a Virus: The Rhetoric of Scientifıc Discovery Accounts,” in Landmark Essays on Rhe…