Based on an action research project implemented at two South African universities, we argue that content and language integration (ICL) collaborative partnerships benefit not only from collaboration between language and content specialists, but in addition, from collaboration between language specialists, general education specialists and content specialists from a variety of disciplines. However, as we illustrate below, these benefits may be accompanied by substantial challenges. We make a further claim, for the value of a transformative approach towards collaboration for content and language integration, in which the teacher/researchers engage in their practice in a critical and reflexive manner, and by so doing, foster their own deep learning, as well as the deep learning of the students.