This article investigates service-learning practices and pedagogy at Jackson State University (JSU), a Historically Black University, founded in 1877 to educate underserved and underrepresented African Americans in Mississippi. As a reflection of the university’s motto, “Challenging Minds and Changing Lives,” this research highlights JSU’s concerted efforts to foster students’ participation in school-community literacy partnerships. Since 2009, the university has facilitated academic instruction in first-year English Composition and Literature courses and in second-year Humanities courses. Not only have these efforts enabled JSU students to partner with Elementary schools and African American women’s help initiatives in the Metro-Jackson area, but JSU students have also completed service-learning projects in Limon, Costa Rica. To further illustrate JSU’s commitment to African American literacy partnerships, the authors present a selection of course materials to demonstrate course designs dedicated to service-learning and African American community literacy partnerships.