The discoveries of science and technology are accelerating. The choice of how to regulate and react to scientific and technological innovations relies heavily on the notion of risk. The emergence nature contemporary science and technology (i.e., complex systems that are not reducible to the simple physical and chemical processes from which they arose) confounds risk studies Indeed, whether to embark on a particular path of scientific inquiry or proceed with a technological development depends on the ability to calculate the amount of risk associated with the endeavor. We are, however, ill-equipped to resolve the demands of risk analysis with certainty.