Successfully engaging in a health- or medical-related activity is a matter of understanding what one needs to do. This means information used in this context needs to be easy to use. Accomplishing the goals laid out in the essay will facilitate understanding and allow for effective use. Thus, successful medical and health communication are connected to one central concept: usability. But how to achieve this goal? The answer is through patient-focused design practices that help mirror the experiences of patients who are using such materials. This entry overviews such an approach - which I call patient experience design (PXD) - and explains why such an approach is central to best health and medical communication practices.