Abstract
The article consists of four sets of questions designed to help the author, reviewer, and editor examine the medical/scientific manuscript from four different aspects: 1) its medical/scientific contribution to its field (Gross Examination); 2) contents and coverage of topic (In-depth Examination); 3) rhetoric and punctuation (Minute Examination); and 4) the manuscript-package assembled for transmission to journal editor (Components of the Manuscript). When such examinations are used one at the time as needed, they will help individuals to separate content from mechanics of presentation and to distinguish scientific evidence from erroneous speculation. They will also help authors, reviewers, and editors to judge objectively the scientific worthiness of the paper, to improve the literary presentation, and to elevate the quality of effective medical/scientific communications.